CEACAM5 and breast carcinoma: Based on the changes of the above indicators, when conducting a routine physical examination or breast cancer screening, considering the cost performance, it is recommended to use the top three of the three combinations: AFP + CEA + CA153 and AFP + CA153 + CA125, with had the highest accuracy (80.25%), or CEA + CA125 + CA199, which had the highest AUC value (0.922).