PTPN23 and neurodevelopmental disorder: For example, in NEDBASS (neurodevelopmental disorder and structural brain anomalies with seizures and spasticity) patient materials several different nonsense and missense mutations in HD-PTP have been detected (Alazami et al., 2015; Sowada et al., 2017; Trujillano et al., 2017; Smigiel et al., 2018; Bend et al., 2020).