Initially, associations of PTPRJ SNPs with colorectal cancer (CRC) susceptibility were reported (Mita et al., 2010) but, as for PTPN12, systematic review of available data led to the conclusion that there is no significant association of PTPRJ variants with hereditary colorectal cancer (Belhadj et al., 2020). The gene discussed is PTPRJ; the disease is familial colorectal cancer.