More recently, a large-scale meta-analyses of GWAS studies aimed at Alzheimer’s disease (AD) remained without genome-wide significant associations, but the combination with hippocampal transcriptomic data allowed for a transcriptome-wide association study that pointed to PTPN9 as one out of 24 genes that could affect hippocampus-dependent AD development (Liu et al., 2021b). Here, PTPN9 is linked to Alzheimer disease.