PTPRK and Hereditary breast and ovarian cancer syndrome: Adding to the puzzle, in the ClinVar database PTPRK mutations have been associated with hereditary breast and ovarian cancer (p.R1398Q; VCV000981859) and with metastasis from primary bronchial carcinoid tumor (VCV000916695) but these may also affect PTPRK-AS1, the antisense transcript that is derived from the complementary strand.