Behavioral pathologies are also mirrored in IA-2β deficient mice (Nishimura et al., 2009), and this connection with hearing defects is corroborated by the identification of rs10081191 in PTPRN2 being associated with noise-induced hearing loss in a Chinese cohort (Niu et al., 2021). The gene discussed is PTPRN2; the disease is hearing loss disorder.