EGFR and chronic lung disease: Further studies revealed that this rare nonsynonymous variant (p.N370K, in the fourth FNIII domain of GLEPP1) attenuated EGFR signaling in response to several stimuli in primary epithelial cells (Radder et al., 2017), which fits with earlier reports on a link between the EGFR pathway and chronic lung diseases (Vallath et al., 2014).