Univariate regression analysis revealed that 30 of the 55 cuproptosis-associated lcnRNAs screened from the ccRCC cohort, such as RAP2C-AS1, SUCLG2-AS1, PAXIP1-AS2, and LlNC01534, were strongly associated with the prognosis of ccRCC (Figure 2A). The gene discussed is RAP2C; the disease is nonpapillary renal cell carcinoma.