Aminooxyacetate is a pan-aminotransferase inhibitor that potently repressed the growth of PIK3CAp110α mutant xenograft CRC tumors, and the antitumor effect of aminooxyacetate on PIK3CAp110α-mutant xenograft tumors has been proven to be due to the inhibition of GPT2 [89]. Here, GPT2 is linked to colorectal carcinoma.