PTEN and Familial prostate cancer: LINC00861 has also been identified as a protective factor in ovarian cancer, as a competing endogenous RNA for miR-513b-5p in cervical cancer that regulates the PTEN/AKT/mTOR signaling pathway to inhibit cervical cancer cell progression and as being closely associated with PD1, PD-L1, and CTLA4 in prostate cancer [38–40].