Cluster C was similar to A, with significant enrichment of pathways related to immune activation and tumor suppressor pathways and pathways related to cancer progression, such as P53 and apoptosis, INFα and IL2/STAT5 pathways, PI3K/AKT/mTOR, IL2/STAT5 signaling, and MTORC1. The gene discussed is AKT1; the disease is neoplasm.