FZD1 and glioblastoma: The two DEmRNAs were FZD1 and KLF10 and were inversely correlated with overall survival, as is shown in Fig. 8A, B. To better understand the roles of two hub genes in the GBM immune microenvironment, we analyzed the association between FZD1, KLF10, and several common immune cell types in the TIMER database.