TIPE3 and colorectal carcinoma: These prognostic factors were then subjected to multivariate regression analysis, and the results showed that the TIPE3 expression in adjacent normal tissues (HR = 3.215, 95% CI: 1.569–6.586, p=0.0014), the number of CD8+ T cells in adjacent normal tissues (HR = 0.387, 95% CI: 0.184–0.813, p = 0.0122), and the number of CD66b+ neutrophils in adjacent normal tissues (HR = 2.474, 95% CI: 1.036–5.905, p = 0.0413) were prognostic factors affecting the OS rate of CRC patients.