In a previous PICU study, univariate logistic regression analysis showed that a low APOA5 level was an independent risk factor for PICU mortality in pediatric patients with sepsis.15 Furthermore, multivariate logistic regression analysis in another PICU study revealed that PSP was an independent factor in the prognosis of sepsis in pediatric patients.23 Elevated copeptin levels in patients were also associated with an increased risk of mortality16 and were predictive of mortality in critically ill patients with sepsis.28 The gene discussed is APOA5; the disease is Sepsis.