To examine whether the Bax gene might be silenced at the epigenetic level in the 560 R2.2 lymphoma cells in which Bax transcripts could not be detected, we treated these cells with the hypomethylating agent 5’azacytidine, which inhibits DNMT1, and performed qRT-PCR to look for the restoration of Bax mRNA expression levels (Fig. 5C). The gene discussed is DNMT1; the disease is lymphoma.