Both SNP studied are in the promoter region of the CDH1 gene which means that these polymorphisms may lead to over or under-expression of the e-cadherin and thus could have a correlation with the pathogenesis of vitiligo.6, 7 Patients with a clinical diagnosis of vitiligo and healthy controls without a family history of vitiligo were recruited at the Dermatology Department of the University Hospital “Dr. This evidence concerns the gene CDH1 and vitiligo.