As shown in Fig 1A, the relative SOCS3 protein levels in HCMV- versus mock-infected NPCs increased dramatically at 4 hours post-infection (hpi) to 4.3-fold, quickly dropped to 2.1-fold at 8 hpi, and then slowly rose to 2.6-fold at 96hpi. The gene discussed is SOCS3; the disease is infection.