NLRP3 and acute monocytic leukemia: Furthermore, Satoh et al. (2014) [30] note that rosuvastatin (0.4–10 μM) can also significantly reduce the levels of IL-1β and NLR family pyrin domain containing 3 (NLRP3) in human monocytic cell lines derived from an acute monocytic leukemia patient (THP-1 cells) subjected to oxidative stress.