Specifically, in hepatocellular carcinoma, fetal‐derived macrophages characterized by expression of folate receptor beta (FOLR2) promote vascularization, proliferation, and an immuno‐suppressive environment through selective interaction with endothelial cells expressing Plasmalemma Vesicle Associated Protein (PLVAP), a marker of fetal liver endothelium.244. The gene discussed is FOLR2; the disease is hepatocellular carcinoma.