We then transfected GFP-LC3 into ovarian cancers cells, and found that FGF19 downregulation and BIRB796 treatment decreased the formation of GFP-LC3 puncta, while FGF19 upregulation and IFN-γ treatment increased the formation of GFP-LC3 puncta (Figs. 4E–4H). This evidence concerns the gene IFNG and ovarian carcinoma.