These levels were all significantly increased in the tumor tissue of the water-treated group compared with those in the normal thigh tissues of UTR mice (p<0.01) and significantly decreased in the tumor tissues of EDX-treated group compared with the water-treated group (p<0.01).Fig. 4Bshows the immunofluorescence data showing the expression of STAT3, cyclin D1, and Ki67 in the normal tissues of UTR mice and in the tumor tissues of water- or EDX-treated Colon26-inoculated mice. Here, STAT3 is linked to neoplasm.