In this study, we enrolled stage II/III breast cancer patients and measured the levels of pro-inflammatory cytokines (TNF-α, IFN-γ, GM-CSF) and oxidative stress markers (antioxidant enzymes: SOD and catalase, pro-oxidant: MDA and NO) in the serum along with QoL and symptomatic scale at baseline, 16, 32, and 48 weeks and compared them with patients who were not performing the yoga. This evidence concerns the gene TNF and breast cancer.