CD274 and neoplasm: We examined the immune environment of the tumor samples using immunohistochemistry for TILs and key checkpoint molecules expressed by T cells, that is, CTLA‐4A and PD‐1, as well as CD68+ macrophages and checkpoint molecules that can be expressed by macrophages, other innate immune cells, tissue and tumor cells, that is, PDL‐1 and GAL‐9A (Table 3).