LGALS9 and neoplasm: GAL‐9 ligates with T‐cell immunoglobulin and mucin protein‐3 (TIM‐3), a cell surface inhibitory receptor found mainly on activated CTLs and CD4+ T cells, as well as PD‐1 leading to T‐cell apoptosis thereby preventing T cell‐mediated tumor cell elimination.15, 16, 17