For instance, iron-induced lipid peroxidation was shown to inhibit dopamine synthesis [155], while the activity of monoamine oxidase B (MAO-B), which plays a major role in catalysing dopamine degradation in the adult cortex [156, 157], is markedly enhanced by iron [158], providing mechanistic links between iron accumulation and the increasingly appreciated role of cortical hypodopaminergia in schizophrenia [159, 160]. Here, MAOB is linked to schizophrenia.