As demonstrated in GEPIA (http://gepia2.cancer-pku.cn/) database, PDHB-AS was remarkably down-regulated (P < 0.05) in 306 specimens of cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) in relative to 13 normal tissues (Fig. 1A). This evidence concerns the gene PDHB and endocervical adenocarcinoma.