To elucidate the partnership of MARVELD1 and PARP1 in cancer chemo-resistance, the expression of MARVELD1 and PARP1 protein was assessed in a normal colorectal epithelial cell line (NCM460) and a panel of CRC cell lines (DLD1, HT29, LS174T, T84, HCT15, HCT116, LoVo, RKO) (Supplementary Fig. S6b). The gene discussed is MARVELD1; the disease is cancer.