The potential relationships among the expression of RBM3, β-catenin and METTL3 was also observed in human PCa tissue samples, in which RBM3 was strongly stained when β-catenin was weakly expressed, whereas METTL3 was always strongly expressed (Fig. 4f), supporting the involvement of METTL3 in the regulation of β-catenin by RBM3. This evidence concerns the gene METTL3 and posterior cortical atrophy.