MLX and T-cell leukemia: The in-cellulo editing activityof the modified MAD7 nuclease was determined by nucleofection of RNPsin a T-cell leukemia cell line (Jurkat), followed by amplificationof the edited part of the locus, targeted next-generation sequencingfor identification of the edits, and finally computational analysisof modification frequency using the CRISPResso2 algorithm.26