However, this does not seem to be the case, as preliminary analysis of complemented, gL-deleted RhCMV recombinants (53) indicates that single-cycle 68-1 RhCMV/SIV vectors blocked at the stage of new cell infection, but after a normal late stage, retained the ability to elicit unconventional CD8+ T cells and protect against SIV challenge (our unpublished observations). The gene discussed is CD8A; the disease is infection.