SFTPB and papillary adenocarcinoma: Within this context, the cell line NCI‐H441 that was generated from a male patient with a papillary adenocarcinoma also demonstrated mixed characteristics of club cell‐like and AT‐2‐like cells.[92] While the presence of SFTPA and SFTPB was detected in these early studies, also the AT‐1 relevant marker RAGE has been reported to be expressed by NCI‐H441 in later studies.[93] Similar to the polyclonal hAELVi cell line, also for NCI‐H441 no clonal selection was performed, which a study by Neuhaus et al.