In mothers without hypercholesterolemia, higher maternal HDL-C and apoA1 levels were associated with a lower increase in offspring body weight from 9 months to 8 years of age (Pinteraction < 0.001 for both), higher maternal apoB/apoA1 ratio was associated with a larger increase in offspring body weight from 9 months to 8 years of age (Pinteraction = 0.001), while maternal TG level was inconsistently associated with offspring body weight up to 8 years of age (Pinteraction < 0.001). The gene discussed is APOB; the disease is familial hypercholesterolemia.