SLFN5 and ovarian carcinoma: To investigate the role of SLFN5 in ovarian cancer cells, MTT assay was performed, and the results showed that cell proliferation was significantly inhibited in the si-SLFN5#1 and si-SLFN5#2 transfected groups compared with that in the si-NC transfected group (Fig. 5B; P < 0.01).