Next, we detected SLFN5 expression in normal ovarian epithelium cell lines (IOSE80) and ovarian cancer cell lines (OVCAR3, HO-8910, and SKOV3) and noticed that the expression of SLFN5 was significantly higher ovarian cancer cell lines, A2780 cells had the lowest expression of SLFN5 while OVCAR3 cells had the highest expression. Here, SLFN5 is linked to ovarian cancer.