In contrast, TGF-β and interleukin-1 (IL-1) are important players in the development of lung fibrosis, further suggesting an inhibitory role of Thy-1+ (CD90+) fibroblasts in the process of lung fibrosis (Silvera et al. 1994; Tan et al. 2019). The gene discussed is TGFB1; the disease is pulmonary fibrosis.