THY1 and Alzheimer disease: That is, AD-MSCsFGF1 (CD90 fibroblast dominant) effectively secreted functional FGF1 to promote angiogenic proliferation (Hoseini et al. 2017; Jacobs et al. 2016; Bourgine et al. 2019), suggesting that CD90+ fibroblasts in stromal cells might induce angiogenesis and promote cell proliferation by secreting multiple functional cytokines (Fig. 1).