NLRP3 and Parkinson disease: MLT also attenuated neuroinflammation in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced model of Parkinson’s disease through the suppression of microglial activation, downregulation of the NLRP3 inflammasome components, and inhibition of IL-1β secretion71.