In 2010, an randomized controlled trial(RCT) study of 60 patients with PCOS showed that E2 levels on HCG day were significantly negatively correlated with AMH levels among different groups (< 2.54 ng/ml, 2.54–3.85 ng/ml, and > 3.85 ng/ml AMH)56. Here, AMH is linked to polycystic ovary syndrome.