ERBB2 and gallbladder adenosquamous carcinoma: One patient had adenosquamous carcinoma of the gallbladder harbouring a HER2 S310F mutation whose disease had progressed on gemcitabine + cisplatin, 5-fluorouracil/folinic acid + oxaliplatin, and 5-fluorouracil/folinic acid + irinotecan (Fig. 5).