CALCA and autoimmune disease: KC;iASPPΔ8/Δ8 pancreatic neoplasias had increased infiltration of Treg cells (Fig. 3C) and CD8 cells, but not CD4 cells (Fig. S3), suggesting that as in autoimmune disease, iASPP deficiency promotes Treg cell infiltration over conventional CD4 T cell infiltration in pancreatic neoplasia.