To test whether iASPP deficient oncogenic Kras-driven pancreatic cancer maintains an immunosuppressive microenvironment in the presence of a canonical inflammatory insult [64], we subjected KC;iASPPΔ8/Δ8 mice to caerulein-induced chronic pancreatitis (Fig. 4A). Here, PPP1R13L is linked to familial pancreatic carcinoma.