To explore the role of NEO1 in cancer, we first analyzed the expression of Neogenin in eight tumor models, including tumor colon, glioma, tumor lung, kidney renal clear cell carcinoma, neuroblastoma, liver hepatocellular carcinoma, tumor breast, and melanoma, from TCGA and other public databases (Supplementary Table S5). This evidence concerns the gene NEO1 and neoplasm.