CD4 and cytomegalovirus infection: Lillery et al. investigated the specific lymphoproliferative response (LPR) and intracellular cytokine (interferon[IFN]–γ and interleukin [IL]–2) production during the first year after primary CMV infection in 49 pregnant women, finding that transmitter mothers presented a significantly delayed development of the CD4+ T-cell LPR, compared with those who did not [8].