ANXA1 and pancreatic neoplasm: In addition, Annexin A1 (ANXA1) is a ubiquitous protein involved in different processes, as calcium signaling, inflammation, cell proliferation, apoptosis or tumor progression, and which upregulation has been associated with tumor proliferation in breast, bladder, endometrial, colorectal, lung and pancreatic cancer, and melanoma [70–74].