The top 10 secreted factors in the MMD-hemorrhagic group were very similar to MMD-ischemic group, including PDGF-BB, RETN, IL-7, CCL5/RANTES, PAI-1, ICAM1, IL-2, EGF, Chemokine C-X-C motif ligand 10 (CXCL10/IP10), and Eotaxin (Fig. 2B). This evidence concerns the gene SERPINE1 and multiminicore myopathy.