PALM and coronary artery disorder: For lipid traits including high density lipoprotein (HDL), low density lipoprotein (LDL) and their closely related disease—coronary artery disease (CAD), rs799160 and rs892161 identified only by PALM-D2 were confirmed to be HDL-associated SNP and LDL-associated SNP, respectively (Klarin et al., 2018; Sinnott-Armstrong et al., 2021); risk SNP rs7947761 reported by PALM-D2 was confirmed by a recent CAD GWAS (Van Der Harst and Verweij, 2018).