HLA-C and myeloid sarcoma: At present 1961 non-MHC variants in 156 genomic regions are significantly associated with MS and 21% of intergenic variants are associated with gene regulation in cortex tissue but not in immune cells (International Multiple Sclerosis Genetics Consortium, 2019) showing that c-organoids might be a very useful tool to study the effect of MS genetic variants on human corticogenesis.