CXCL12 and laryngotracheoesophageal cleft: Then, we analyzed the potential communication between CSFs and other cell types using cell-cell communication analysis, and found that CSFs might interact with T cells and macrophages through the secretion of chemokines such as CXCL12 in OVC, LC, and PDAC (Figure 3D; Supplementary Figures S3A, B).