PGM5 and malignant colon neoplasm: In addition, a recent report identified lncRNA PGM5 antisense RNA 1 (PGM5-AS1) as a prognostic indicator correlated with better OS in colorectal cancer patients treated with oxaliplatin, and exosomes loaded with PGM5-AS1 and oxaliplatin indeed inhibited the proliferation, metastasis, and acquired resistance to oxaliplatin of colon cancer cells (Hui et al., 2022).