In the present study, univariate analysis results (HR = 3.97, 95% CI = 3.211–4.909, p < .001) showed that TMEM60 is a risk factor for glioma patients in TCGA, whereas multivariate analysis results (HR = 1.32, 95% CI = .935–1.868) were not statistically significant. The gene discussed is TMEM60; the disease is central nervous system cancer.