Moreover, this study showed several T2D/AD common genes predicted to be targeted by hsa-mir-103a-3p downregulated, including MDH1, PTPN3, POLR2C, MYCN, ACTR3B, UBE2D4, SH2D3C, CYCS, ATXN10, ENO2, XRCC6, RRAGA, BCAS2, MKKS, UBL3, UQCRC2, CCT7, MRPL48, HLF, PARP2, ATP6V0B, MDH2, SNCA, RAD51C, UTP18, MADD, TGFBR3, LAMTOR3, RHBDD3, and NPTX2. Here, MADD is linked to Alzheimer disease.