Moreover, this study showed several T2D/AD common genes predicted to be targeted by hsa-mir-103a-3p downregulated, including MDH1, PTPN3, POLR2C, MYCN, ACTR3B, UBE2D4, SH2D3C, CYCS, ATXN10, ENO2, XRCC6, RRAGA, BCAS2, MKKS, UBL3, UQCRC2, CCT7, MRPL48, HLF, PARP2, ATP6V0B, MDH2, SNCA, RAD51C, UTP18, MADD, TGFBR3, LAMTOR3, RHBDD3, and NPTX2. This evidence concerns the gene PARP2 and type 2 diabetes mellitus.