Ding et al. constructed and validated a reliable diagnostic model for CAD based on the expression profiles of 16 ferroptosis-related genes, including ZFP36, VDAC2, TNFAIP3, SCP2, RPL8, PIK3CA, PCBP1, MTDH, MIF, MAP1LC3B, HIF1A, FTH1, CASP8, BACH1, ATP5MC3, and ACSL1, and its AUC value was 0.971 [18]. Here, PIK3CA is linked to coronary artery disorder.