These include Coffin-Siris syndrome (ARID1B), Koolen-de Vries syndrome (KANSL1), Kabuki syndrome (WDR5), and Kleefstra syndrome (WDR5) (Nakagawa and Xiong, 2011; Koolen et al., 2016; Ka et al., 2022; Moffat et al., 2022). Here, WDR5 is linked to Coffin-Siris syndrome.