CYP27B1 and gnathodiaphyseal dysplasia: While we failed to collect biochemical index of 25(OH)D3 from in the Han GDD patient, Ano5KI/KI mice manifested higher calcitriol levels in serum and Cyp27b1 expression in kidneys than wild type mice, which indicated that the generation of calcitriol from 25(OH)D3 was facilitated.