The results from the DiseaseMeth database further proved that KIF11 promoter is hypomethylated in bladder cancer, germ cell cancer, BLCA, ESCC, PAAD, HNSC, KICH, KIRC, LAML, LGG, OSC, OV, UCS, PA, PRAD, READ, and COAD and hypermethylated in gastric cancer, malignant pluripotent embryonal carcinoma, CHOL, ESCA, MM, GBM, LUSC, PCPG, and UCEC (Supplementary Figure 4). This evidence concerns the gene LSS and pancreatic adenocarcinoma.