Analysis of the correlation between KIF11 expression and stemness indices, including mRNA expression-based stemness index (mRNAsi), epigenetically regulated-mRNA expression-based stemness index (EREG-mRNAsi), DNA methylation-based stemness index (mDNAsi), differentially methylated probes-based stemness index (DMPsi), enhancer elements/DNA methylation-based stemness index (ENHsi), and epigenetically regulated DNA methylation-based stemness index (EREG-METHsi), revealed that KIF11 expression correlated positively with cancer stemness in almost all human cancer types except THYM. The gene discussed is KIF11; the disease is cancer.