KIR3DL1 and acute myeloid leukemia: In another study, a cohort of AML patients treated with autologous HSCT described a lower incidence of relapse due to the low-affinity interactions (KIR3DL1+ and HLA-Bw4-80T+, HLA-Bw4-80I− genotypes) compared to a genotype with high-affinity interactions (KIR3DL1+ and HLA-Bw4-80I+ genotype) and this effect was also induced by a HLA-Bw4 copy number (106).