AIM2 and psoriasis: Our meta-analysis of 76 psoriasis-related SNPs in the Exome Asian array and Exome Fine array and replication phase identified 11 variants in 11 different new susceptibility genes located in nonhuman leukocyte antigen (HLA) regions, including AIM2 (rs2276405, P=3.22 × 10−9, odds ratio (OR) =0.83), which is a stop-gain gene variant locus (Figure 1B) (43).