CD8A and chronic myelogenous leukemia, BCR-ABL1 positive: For the exhausted and senescent molecular expression pattern, we found that the level of PD-1+CD8+ T cells was significantly increased in DN-CML (25.3% vs 16.5%, P = 0.0231), TKI-F (24.6% vs 16.5%, P = 0.0076), and MR (23.8% vs 16.5%, P = 0.0016) patients when compared with HIs (Figure 1F).