PDCD1 and acute graft versus host disease: We explored the clinical outcome after alloHSCT according to the combined LAG-3 rs870849 and PD1.1 rs36084323 genotype of the donor, and we detected that the LAG-3 rs870849 TT genotype is associated with the highest severe acute GVHD incidence and TRM, leading to a worse OS and DFS, independently of the PD-1 rs36084323 genotype.