NFKB1 and celiac disease: In addition, mapping of expression quantitative trait loci (eQTL), signaling pathway analyses, and functional SNP analyses have established associations between celiac disease and T cell receptor (TCR), NFκB, and interferon (IFN) signaling pathways and several candidate genes like UBASH3A, CD28, CSK, CD274, SH2B3, and STAT4 (49–51).